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Synonyms: DBCO PEG Carbonylacrylic acid, Carbonylacrylic acid PEG5k DBCO, Carbonylacrylic PEG DBCO
Product Description:
Carbonylacrylic PEG DBCO is one of Nanocs' thiol reactive PEG derivatives that have a terminal DBCO group which can go Copper free Click Chemistry. Similar to Maleimide, carbonylacrylic group reacts with thiol group quickly to form a stable thiol ether bond via so called ene-thiol Michael addition. Unlike maleimide-thiol adduct, the reaction between carbonylacrylic acid and thiol is non-reversible, and therefore the adduct is more stable for carbonylacrylic acid thiol conjugate. Carbonylacrylic acid reagents have been excellent reagents for site-specific Cysteine modification. DBCO, on the other hand, can react to azide group via Click Chemistry without need copper catalyst.
Product Specifications:
- Form: Solid
- Apearance: Light yellow
- Reactive groups: Carbonylacrylic and DBCO
- Reactive to: Sulfhydryl and azide groups
- Solubility: Soluble in water
Storage:
- Store at -20 0C. Desiccate.
Nanocs 的产品包括功能化生物聚合物、纳米颗粒、标记蛋白质、抗体、酶、肽和核苷酸。我们还为荧光标记、聚乙二醇化、生物素化和生物共轭提供丰富的阵列反应性分子。
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